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2023年4月19日 Cryoelectron microscopy structures reveal how XPC recognizes DNA lesions and recruits XPA and the TFIIH core complex for lesion verification in nucleotide
互补组 C 型色素性皮肤病又称 XPC,是一种人体中由XPC基因编码的蛋白质。 XPC 参与核苷酸切除修复过程中对大块 DNA 加合物的识别。 它位于3号染色体上 。
核苷酸切除修复(nucleotide excision repair, NER)是一种修复由紫外线和化学致癌物引起的各种DNA损伤的重要机制。 许多被 诊断 为着色性干皮病(xeroderma pigmentosum,
2018年7月4日 The DNA damage sensor XPC is involved in nucleotide excision repair Here we show that in the absence of damage, XPC co
Xeroderma pigmentosum, complementation group C, also known as XPC, is a protein which in humans is encoded by the XPC gene XPC is involved in the recognition of bulky DNA adducts in nucleotide excision repair It is located on chromosome 3
互补组 C 型色素性皮肤病 又称 XPC,是一种人体中由 XPC 基因 编码的 蛋白质 。 XPC 参与 核苷酸切除修复 过程中对大块 DNA 加合物的识别。
2018年7月4日 Our data reveal that the DNA repair factor XPC is also an RNA polymerase II cofactor recruiting the ATAC coactivator complex to promoters by interacting with the
2022年8月13日 Our work identifies a novel XPCPARP axis that links ALC1mediated chromatin remodeling to global genome nucleotide excision repair (Fig 9e) Proteomic
This study provides novel insights into transcriptional regulation of the stem cell state by characterizing interactions between key transcription factors SOX2 and OCT4, and a recently identified, multifunctional, stem cell
2018年7月4日 The DNA damage sensor XPC is involved in nucleotide excision repair Here we show that in the absence of damage, XPC colocalizes with RNA polymerase II
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2014年6月23日 — In the global genome nucleotide excision repair (GGNER; left) subpathway, the damage sensor XPC, in complex with UV excision repair protein RAD23 homologue B (RAD23B) and centrin 2 (CETN2
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该基因编码核苷酸切除修复(ner)途径的一个组成部分。 ner通路涉及多种成分,包括着色性干皮病(xp)ag和v、科凯恩综合征(cs)a和b、毛发硫营养不良(ttd)a组等。 该成分xpc在全球基因组 ner 的早期步骤,特别是损伤识别、开放复合物形成和修复蛋白复合物形成。
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2018年7月4日 — The DNA damage sensor XPC is involved in nucleotide excision repair Here we show that in the absence of damage, XPC colocalizes with RNA polymerase II (Pol II) and active posttranslational histone modifications marks on a subset of class II promoters in human fibroblasts XPC depletion triggers s
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插拔式连接器, 额定横截面: 15 mm 2 , 颜色: 黑色, 额定电流: 8 A, 额定电压(III/2): 160 V, 触点表面: 锡, 触点类型: 孔式插头, 行数: 1, 位数: 3, 产品系列: XPC 1,5/ST, 针距: 35 mm, 接线方式: PushX连接, 导线/PCB连接方向: 0 °, 锁扣: 不带锁扣, 插拔系统: COMBICON MC 1,5, 互锁: 不带, 安装
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2018年7月4日 The DNA damage sensor XPC is involved in nucleotide excision repair Here we show that in the absence of damage, XPC colocalizes with RNA polymerase II (Pol II) and active posttranslational
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该基因编码核苷酸切除修复(ner)途径的一个组成部分。 ner通路涉及多种成分,包括着色性干皮病(xp)ag和v、科凯恩综合征(cs)a和b、毛发硫营养不良(ttd)a组等。 该成分xpc在全球基因组 ner 的早期步骤,特别是损伤识别、开放复合物形成和修复蛋白复合物形成。
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the absence of damage, XPC colocalizes with RNA polymerase II (Pol II) and active post translational histone modifications marks on a subset of class II promoters in human fibro blasts
xpc有潜力处理各种各样的dna损伤,同时它也能结合到没有任何损伤的dna位点,比如碱基错配。由于在这种不适当的位点进行不必要的修复反应可能会增加不良突变的风险,因此必须验证是否有任何必须修复的损伤。
The Apple IIWhen it debuted in 1977, the Apple II was promoted as an extraordinary computer for ordinary people The userfriendly design and graphical display made Apple a leader in the first decade of personal computingUnlike the earlier Apple I, for which users had to supply essential parts such as a case and power supply, the Apple II was a fully